Ghrelin Cells in the Pancreatic Islet / Single Project

Media Details

Media ID: SYM0051
Client: Scientific
Created on: 2005-02-01
Published on: 2014-09-23
Dimensions: 162 x 2700 pixels

Type: Infographic

Audiences: Scientific

Keywords: infographics, illustration, pancreas, diabetes, ghrelin, hormone, epsilon cells, endocrine, graphics, pancreas

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  • Ghrelin Cells in the Pancreatic Islet

Description

The four major cell types within the Islet of Langerhans are shown in the central panel, with the most recently discovered ghrelin-producing Epsilon-cell. The islet on the left illustrates an idealized distribution of alpha, beta, gamma and PP cells. The islet on the right represents an islet that includes Epsilon-cells (purple). Note that the Epsilon-cells are located on the periphery of the islet.

References

Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc Natl Acad Sci U S A. 2004. 101(9):2924-9